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https://repository.cihe.edu.hk/jspui/handle/cihe/846| Title: | An eigen-binding site based method for the analysis of anti-EGFR drug resistance in lung cancer treatment | Author(s): | Wang, Debby Dan | Author(s): | Ma, L. Zou, B. Yan, H. |
Issue Date: | 2017 | Publisher: | IEEE | Journal: | IEEE/ACM Transactions on Computational Biology and Bioinformatics | Volume: | 14 | Issue: | 5 | Start page: | 1187 | End page: | 1194 | Abstract: | We explore the drug resistance mechanism in non-small cell lung cancer treatment by characterizing the drug-binding site of a protein mutant based on local surface and energy features. These features are transformed to an eigenbinding site space and used for drug resistance level prediction and analysis. |
URI: | https://repository.cihe.edu.hk/jspui/handle/cihe/846 | DOI: | 10.1109/TCBB.2016.2568184 | CIHE Affiliated Publication: | Yes |
| Appears in Collections: | HS Publication |
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