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Title: An eigen-binding site based method for the analysis of anti-EGFR drug resistance in lung cancer treatment
Author(s): Wang, Debby Dan 
Author(s): Ma, L.
Zou, B.
Yan, H.
Issue Date: 2017
Publisher: IEEE
Journal: IEEE/ACM Transactions on Computational Biology and Bioinformatics 
Volume: 14
Issue: 5
Start page: 1187
End page: 1194
We explore the drug resistance mechanism in non-small cell lung cancer treatment by characterizing the drug-binding site of a protein mutant based on local surface and energy features. These features are transformed to an eigenbinding site space and used for drug resistance level prediction and analysis.
DOI: 10.1109/TCBB.2016.2568184
CIHE Affiliated Publication: Yes
Appears in Collections:HS Publication

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