Please use this identifier to cite or link to this item: https://repository.cihe.edu.hk/jspui/handle/cihe/793
Title: Molecularly imprinted polymer based on MWCNTs-QDs as fluorescent biomimetic sensor for specific recognition of target protein
Author(s): Bligh, Annie Sim Wan 
Author(s): Ding, Z.
Tao, L.
Quan, J.
Nie, H.
Zhu, L.
Gong, X.
Issue Date: 2015
Publisher: Elsevier
Journal: Materials Science and Engineering: C 
Volume: 48
Start page: 469
End page: 479
Abstract: 
A novel molecularly imprinted optosensing material based on multi-walled carbon nanotube-quantum dots (MWCNT-QDs) has been designed and synthesized for its high selectivity, sensitivity and specificity in the recognition of a target protein bovine serum albumin (BSA). Molecularly imprinted polymer coated MWCNT-QDs using BSA as the template (BMIP-coated MWCNT-QDs) exhibits a fast mass-transfer speed with a response time of 25 min. It is found that the BSA as a target protein can significantly quench the luminescence of BMIP-coated MWCNT-QDs in a concentration-dependent manner that is best described by a Stern–Volmer equation. The KSV for BSA is much higher than bovine hemoglobin and lysozyme, implying a highly selective recognition of the BMIP-coated MWCNT-QDs to BSA. Under optimal conditions, the relative fluorescence intensity of BMIP-coated MWCNT-QDs decreases linearly with the increasing target protein BSA in the concentration range of 5.0 × 10−7– 35.0 × 10−7 M with a detection limit of 80 nM.
URI: https://repository.cihe.edu.hk/jspui/handle/cihe/793
DOI: 10.1016/j.msec.2014.12.032
CIHE Affiliated Publication: No
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