Please use this identifier to cite or link to this item:
https://repository.cihe.edu.hk/jspui/handle/cihe/788
DC Field | Value | Language |
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dc.contributor.author | Bligh, Annie Sim Wan | en_US |
dc.contributor.other | Jin, M. | - |
dc.contributor.other | Spillane, D. E. M. | - |
dc.contributor.other | Geraldes, C. F. G. C. | - |
dc.contributor.other | Williams, G. R. | - |
dc.date.accessioned | 2021-07-07T08:01:31Z | - |
dc.date.available | 2021-07-07T08:01:31Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://repository.cihe.edu.hk/jspui/handle/cihe/788 | - |
dc.description.abstract | The ion exchange intercalation of two Gd-based magnetic resonance imaging contrast agents into hydroxy double salts (HDSs) is reported. The presence of Gd<sup>3+</sup> diethylenetriaminepentaacetate and Gd<sup>3+</sup> diethylenetriaminepenta(methylenephosphonate) complexes in the HDS lattice after intercalation was confirmed by microwave plasma-atomic emission spectroscopy. The structural aspects of the HDS-Gd composites were studied by X-ray diffraction, with the intercalates having an interlayer spacing of 14.5–18.6 Å. Infrared spectroscopy confirmed the presence of characteristic vibration peaks associated with the Gd<sup>3+</sup> complexes in the intercalation compounds. The proton relaxivities of the Gd<sup>3+</sup> complex-loaded composites were 2 to 5-fold higher in longitudinal relaxivity, and up to 10-fold higher in transverse relaxivity, compared to solutions of the pure complexes. These data demonstrate that the new composites reported here are potentially potent MRI contrast agents. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Royal Society of Chemistry | en_US |
dc.relation.ispartof | Dalton Transactions | en_US |
dc.title | Gd(III) complexes intercalated into hydroxy double salts as potential MRI contrast agents | en_US |
dc.type | journal article | en_US |
dc.identifier.doi | 10.1039/C5DT03433G | - |
dc.contributor.affiliation | School of Health Sciences | en_US |
dc.relation.issn | 1477-9234 | en_US |
dc.description.volume | 44 | en_US |
dc.description.issue | 47 | en_US |
dc.description.startpage | 20728 | en_US |
dc.description.endpage | 20734 | en_US |
dc.cihe.affiliated | No | - |
item.fulltext | With Fulltext | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
crisitem.author.dept | S.K. Yee School of Health Sciences | - |
crisitem.author.orcid | 0000-0002-4757-2159 | - |
Appears in Collections: | HS Publication |
Files in This Item:
File | Description | Size | Format | |
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Check Library Catalogue | 115 B | HTML | View/Open |
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