Please use this identifier to cite or link to this item: https://repository.cihe.edu.hk/jspui/handle/cihe/1732
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dc.contributor.authorBligh, Annie Sim Wanen_US
dc.contributor.otherWang, Y.-
dc.contributor.otherKong, L.-
dc.contributor.otherLei, X.-
dc.contributor.otherHu, L.-
dc.contributor.otherZou, H.-
dc.contributor.otherWelbeck, E.-
dc.contributor.otherWang, Z.-
dc.date.accessioned2021-11-15T02:39:33Z-
dc.date.available2021-11-15T02:39:33Z-
dc.date.issued2009-
dc.identifier.urihttps://repository.cihe.edu.hk/jspui/handle/cihe/1732-
dc.description.abstractA comprehensive two-dimensional HPLC system with an immobilized liposome chromatography (ILC) column in conjunction with an RP column (in tandem) was developed for the screening and analysis of the membrane-permeable compounds in a traditional Chinese medicine prescription Longdan Xiegan Decoction (LXD). More than 50 components in LXD were resolved using the developed separation system. Eight flavonoids and two iridoids were identified interacting with the ILC column; a system that mimics biomembranes. The results show that the developed comprehensive two-dimensional chromatography system can be used for identifying membrane permeable natural products in complex matrixes such as extracts of traditional Chinese medicine prescriptions.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of Chromatography Aen_US
dc.titleComprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoctionen_US
dc.typejournal articleen_US
dc.identifier.doi10.1016/j.chroma.2008.05.074-
dc.contributor.affiliationSchool of Health Sciencesen_US
dc.relation.issn0021-9673en_US
dc.description.volume1216en_US
dc.description.issue11en_US
dc.description.startpage2185en_US
dc.description.endpage2191en_US
dcterms.availableInternal Note: CS - B115635-
dc.cihe.affiliatedNo-
item.languageiso639-1en-
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.openairetypejournal article-
crisitem.author.deptS.K. Yee School of Health Sciences-
crisitem.author.orcid0000-0002-4757-2159-
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