Please use this identifier to cite or link to this item:
https://repository.cihe.edu.hk/jspui/handle/cihe/1502| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Bligh, Annie Sim Wan | en_US |
| dc.contributor.other | Wardle, N. J. | - |
| dc.contributor.other | Hudson, H. R. | - |
| dc.contributor.other | Matthews, R. W. | - |
| dc.contributor.other | Nunn, C. M. | - |
| dc.contributor.other | Vella, C. | - |
| dc.date.accessioned | 2021-10-12T03:54:39Z | - |
| dc.date.available | 2021-10-12T03:54:39Z | - |
| dc.date.issued | 2013 | - |
| dc.identifier.uri | https://repository.cihe.edu.hk/jspui/handle/cihe/1502 | - |
| dc.description.abstract | Chemical enhancement: Designed to target HIV-1 protease, a novel γ-hydroxyphosphonate has been found to significantly enhance viral replication in a panel of clinically relevant R5 HIV-1 isolates. This unexpected result constitutes the first instance of a small molecule capable of doing this, and it has implications for the preparation and use of R5 isolates in vaccine and drug development. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Wiley | en_US |
| dc.relation.ispartof | ChemMedChem | en_US |
| dc.title | Enhanced replication of R5 HIV-1 isolates in vitro by a small-molecule reagent targeting HIV-1 protease | en_US |
| dc.type | journal article | en_US |
| dc.identifier.doi | 10.1002/cmdc.201300051 | - |
| dc.contributor.affiliation | School of Health Sciences | en_US |
| dc.relation.issn | 1860-7187 | en_US |
| dc.description.volume | 8 | en_US |
| dc.description.issue | 5 | en_US |
| dc.description.startpage | 719 | en_US |
| dc.description.endpage | 721 | en_US |
| dc.cihe.affiliated | No | - |
| item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
| item.grantfulltext | open | - |
| item.cerifentitytype | Publications | - |
| item.languageiso639-1 | en | - |
| item.fulltext | With Fulltext | - |
| item.openairetype | journal article | - |
| crisitem.author.dept | School of Health Sciences | - |
| crisitem.author.orcid | 0000-0002-4757-2159 | - |
| Appears in Collections: | HS Publication | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Check Library Catalogue | 115 B | HTML | View/Open |
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